ABSTRACT
Objective: To study the therapeutic effect of compound Chinese medicine preparation of wild chrysanthemum and rhizoma drynariae combined with ornidazole in the treatment of chronic periodontitis, to explore the curative effect of this method in the treatment of chronic periodontitis, and to calarify its mechanism. Methods: A total of 112 patients with chronic periodontitis were divided into control group, ornidazole group, Chinese medicine group, Chinese medicine combined with ornidazole group (combination group) according the order of clinic time; there were 28 cases in each group. After basic periodontal treatment of the affected tooth (supragingival scaling and subgingival scaling), the periodontal pockets of the patients in control group were washed with 3% H2O2 and 0. 9%NaCl injection by turns, once a week; the patients in ornidazole group were orally administered with ornidazole one piece at a time, twice a day; the patients in Chinese medicine group were injected with compound Chinese medicine preparation of wild chrysanthemum and rhizoma drynariae into the pocket to make the medicine overflow to the edge of the gingival margin, once a week; the patients in combination group were injected with compound Chinese medicine preparation into the periodontal pocket while orally administered with ornidazole. All patients in various groups were treated for 4 weeks. The periodontal indexes including modified plaque index (mPLI), modified sulcus bleeding index (mSBI), probing depth (PD), and attachment loss (AL) of the patients in various groups were observed before and after treatment; and the levels of tumor necrosis factor-α (TNF-α) and prostaglandin E2 (PGE2) in the gingival crevicular fluid (PISF) of the patients in various groups were detected after one course of treatment. Results: There were no significant differences in the periodontal indexes and the levels of TNF-αand PGE2 in PISF of the patients before treatment between various groups (P>0. 05). Compared with control group, the level of PGE2 in PISF in Chinese medicine group was reduced (P0. 05); the mPLI, mSBI, PD and AL, the TNF-α level in PISF of the patients in combination group were significantly reduced (P<0. 05). Compared with Chinese medicine group, the mPLI, mSBI, PD and AL, the levels of TNF-α and PGE2 in PISF of the patients in combination group were significantly reduced (P<0. 05). Conclusion: The traditional compound Chinese medicine preparation of wild chrysanthemum and rhizoma drynariae combined with ornidazole has the best therapeutic effect in the chronic periodontitis, which can improve the periodontal index and reduce the levels of TNF-α and PGE2 in PISF of the patients.
ABSTRACT
Objective:To discuss the therapeutic effect of related periodontal surgical treatment and aesthetic rerepair in the patient with residual root and crown of anterior teeth induced by unfitting prosthesis and to clarify the curative effect of periodontal surgical treatment and aesthetic re-repair in the anterior teeth area,and to provide guidance for making the program of clinical treatment.Methods:Two years after repair of the anterior teeth of a patient,the restorations loosed;on the one hand the patient had a toothache of chewing food accompanying gingival bleeding,on the other hand the upper labial frenum was too high,furthermore the upper left incisor apical area showed low density images.After the consultation of periodontics,endodontics,prosthodontics and other disciplines doctors,anterior teeth root canal re-treatment and periodontal basic treatment were adopt as well ascrown lengthening combined with labial freneetomy to restore the normal biological width,additionally apply not only guided bone regeneration (GBR) but also platelet rich fibrin (PRF) to repair the defects of apical bone.One month later,provisional restorations were put into use and then three months later permanent repairs were conducted.Results:The corresponding gingival and gingival papilla shape recoverd perfectly and the height of gingiva coordinated with that of adjacent teeth,in the meantime the upper labial frenum attached normally and there was not obvious space between upper incisors;the morphology and function examination of restoration in maxillary anterior region were both well.The follow-up X-ray showed that the bone density of the defect area was the same as that of the peripheral bone without obvious boundaries.Conclusion:The aesthetic repair of thin biotype referring to anterior area,especially in the complicated re-treatment cases,the intervention of the appropriate periodontal surgical treatment is not only beneficial to obtain the obvious short-term effect,but also positive to stabilize longterm effects.
ABSTRACT
Objective:To explore the influence of gallnut extract as a root canal irrigants in the curative effect of chronic periapical periodontitis,and to clarify its mechanism.Methods:A total of 192 patients diagnosed with chronic periapical periodontitis were selected and randomly divided into control group (distilled water),hydrogen peroxide group,sodium hypochlorite group and gallnut extract group (n=48).In the process of root canal treatment,four irrigants were used respectively,then the curative effects 1 week,6 months,12 months after treatment were observed and compared.Results:After root filling treatment,the cold and heat stimulation of the tooth was insensitive in clinical examination,percussion (-),loose degree≤ Ⅰ °,no swollen gums,bleeding on probing (-),no fistula,normal function of the exercise of chewing,decreased or disappeared transmission area in periapical bone in X-ray photo,and those metioned above were considered effective treatment.After 6 months oftreatment,the effective rate in gallnut group was 89.4％,and there were no statistically significant differences compared with hydrogen peroxide group (91.1％) and sodium hypochlorite group (91.5 ％) (P＞0.05),but there was significant difference compared with control group (67.4％) (P＜0.05).After root filling treatment for 12 months,the effective rate in gallnut group was 83.7％ and there were no statistically significant differences compared with hydrogen peroxide group (83.3％)and sodium hypochlorite group (87.8％) (P＞0.05),but the ratio of tooth from improvement to recovery in gallnut group was higher than those in hydrogen peroxide group and sodium hypochlorite group.Conclusion:Gallnut extract as a root canal irrigants has good antibacterial and cleaning effect,and can achieve the aim of curing the chronic root periapical inflammation and preventing the infection.
ABSTRACT
Objective:To investigate the effect of Chinese traditional medicine-Shuanghuangbu combined with Xipayi Mouth Rinse on the periodontal indexes of the peri-implantitis patients,and to detect the curative effect of Shuanghuangbu combined with Xipayi Mouth Rinse in the treatment of peri-implantitis.Methods: A total of 40 patients diagnosed as peri-implantitis were randomly divided into control group and Chinese traditional medicine group (n=20).All of the patients received supragingival scaling and subgingival scaling,and then the peri-implant pocket of the patients in Chinese traditional medicine group were washed with Xipayi Mouth Rinse,while the fine probe slided slowly along the inner wall of peri-implant pocket into the bottom and retained the Shuanghuangbu,and retreated gently and made the medicine overflow the gingival margin.The patients in control group were given 3% hydrogen peroxide and 0.9% sodium chloride injection washed by turns.The indexes of covering modified plaque index (mPLI),probing pocket depth (PPD),modified sulcular bleeding index (mSBI)of the patients in two groups at baseline and after treatment were detected;Whatman# 1 was applied to aspirate the peri-implant sulcus fluid (PISF)which were weighed at baseline and after treatment,and the level of interleukin-1β (IL-1β)in PISF was analyzed by ELISA method.Results:No differences were observed in age,sex,periodontal indexes, weights of PISF and IL-1βlevels of the patients in two groups before treatment (P >0.05).Compared with before treatment,the indexes including PPD,mSBI,mPLI,weight of PISF and IL-1βlevel in PISF of the patients in two groups were decreased after treatment (P < 0.05).After treatment,the differences in mSBI,mPLI,weight of PISF and IL-1β level in PISF of the patients between control group and Chinese traditional medicine group were significant (P <0.05).Compared with control group,the PPD level of the patients in Chinese traditional medicine group was decreased,but the difference was not significant (P >0.05).Conclusion:The curative effect of Chinese traditional medicine-Shuanghuangbu combined with Xipayi Mouth Rinse is obsious,and the treatment can improve the periodontal status and reduce the level of IL-1βin PISF.